Exhibit 99.2

Ticker: MRIC

Investor Presentation

November 3, 2015

Transforming minimally invasive neurosurgery by enabling real-time visualization with MRI

Forward Looking Statements

Certain statements in this presentation may constitute forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements often can be identified by words such as "anticipates," "believes," "could," "estimates," "expects," "intends," "may," "plans," "potential," "predicts," "projects," "should," "will," "would," or the negative of these words or other words of similar meaning. Forward-looking statements by their nature address matters that, to different degrees, are uncertain and involve risk. Uncertainties and risks may cause MRI Interventions' actual results and the timing of events to differ materially from those expressed in or implied by MRI Interventions' forward-looking statements. Particular uncertainties and risks include, among others: demand and market acceptance of our products; our ability to successfully expand, and achieve full productivity from, our sales, clinical support and marketing capabilities; availability and adequacy of reimbursement from third party payors for procedures utilizing our products; the sufficiency of our cash resources to maintain planned commercialization efforts and research and development programs; future actions of the FDA or any other regulatory body that could impact product development, manufacturing or sale; our ability to protect and enforce our intellectual property rights; our dependence on collaboration partners; the impact of competitive products and pricing; the impact of the commercial and credit environment on us and our customers and suppliers; and our ability to successfully complete the development of, and to obtain regulatory clearance or approval for, our ClearTrace system. More detailed information on these and additional factors that could affect MRI Interventions' actual results and the timing of events are described in its filings with the Securities and Exchange Commission. Except as required by law, MRI Interventions undertakes no obligation to publicly update or revise any forward-looking statements made in this presentation to reflect any change in MRI Interventions' expectations or any change in events, conditions or circumstances on which any such statements are based.

MRI Interventions Opportunity

Market

Market is large and growing

55,000 potential ClearPoint procedures across multiple therapies

Navigation System for Multiple Therapies

Electrode placement for Deep Brain Stimulation

Laser Ablation for ablation of epileptic foci or Brain Tumors

Brain Tumor Biopsy for deep seated tumors

Precise Drug Delivery to target lesions

Large Opportunity Attracting Multiple Players

Area of interest to large medical device companies

Medtronic, St. Jude and Boston Scientific investing in neuro market

MRI Scanner Companies embracing MRI-guided therapies

Drug Companies pursuing direct delivery

Uniquely Positioned

Focused commercial effort; FDA/CE approved products

Delivery platform for multiple therapies

Strong, proprietary position

Recent restructuring complete

MRI Interventions:

Real Time MRI Guided Surgery

First-to-market technology platform enabling real-time MRI guided surgery; FDA-cleared, CE-marked and 40+ ClearPoint sites

Focused commercialization of neuro platform underway, gaining traction; recent restructuring complete

Attractive razor/razorblade business model with strong margins

Compatible with all major MRI manufacturers; Interoperability w/ Medtronic, Monteris, neuro products

Strong intellectual property portfolio

Strong management team with extensive medical device commercialization experience: Intuitive, Medtronic, Kyphon, Boston Scientific, Edwards Lifescience, Cordis

Leadership –Significant Med Device Experience

Key Management

Executive

Title

Prior Experience

Frank Grillo

President, CEO

Peter Piferi

COO

Wendelin Maners

VP Marketing

Robert Korn

VP Sales

Hal Hurwitz

CFO

Board of Directors

Kimble Jenkins, Exec Chair

Maria Sainz

Dr. Phillip Pizzo

Pascal Girin

Timothy Richards

Frank Grillo, CEO

Jack Spencer

Charles Koob

Andrew Rooke

Major Investor

Technology: ClearPoint® Neuro Navigation System

Navigation System consisting of Integrated Devices and Software for Real-Time, MRI Guided, Minimally Invasive Neurosurgical Procedures

Visualize

•Identify target

Verify

•Observe progress to target

Confirm

•Confirm precise placement at target

Without ClearPoint, minimally invasive neuro procedures are performed “blind”

Conventional Stereotactic Procedure

ClearPoint Neuro Procedure

No real-time visualization

Next generation platform enabling real time, MRI guided, minimally invasive brain surgery

ClearPoint® Neuro Navigation System

1.5T or 3T MR Scanners, also works in intraop MRI Suites

MRI Safe Disposable Components:

SmartGrid® and SmartFrame® – Integrated ClearPoint Targeting and Trajectory Precision

ClearPoint® Drape provides sterile procedural field in any diagnostic or intraoperative MRI scanner

Emory University Hospital

UCSF Medical Center

University of Pittsburgh Medical Center

Brigham and Women’s Hospital*

* Image courtesy of IMRIS

Integrates with All Major Scanner Platforms

ClearPoint Procedure Overview

Target Selection & Entry Planning

ClearPoint Procedure Overview

SmartFrame® Trajectory Guide

SmartFrame® Hand Controller

Trajectory Alignment & Device Insertion

ClearPoint Procedure Overview

Delivery of Neurological Therapy

Drug Delivery¹

Electrode Placement

Laser Ablation²

(1) Drug Delivery - The SmartFlow® cannula received 510(k) clearance for injection of cytarabine, a chemotherapy drug, to the ventricles or removal of CSF from the ventricles during intracranial procedures. Delivery of other therapeutic agents, and delivery of agents to other areas of the brain, using the SmartFlow cannula is investigational.

(2) Laser Ablation - MR Thermometry is an MRI-based functionality available on most MR scanner platforms and it is a feature built into products from several third party vendors. The ClearPoint system enables MRI-guided procedures and allows physicians to use this inherent MR capability during a procedure.

ClearPoint Hospital Economics

Increase Patients

Better patient experience provides hospitals the opportunity to reach additional patient populations that may otherwise forego surgery

65% of eligible DBS patients refuse treatment, due to fear of surgery⁽¹⁾

Established, Attractive Reimbursement

Move procedures from the more expensive OR to the less expensive MR suite, with equivalent reimbursement

Improved Utilization of Existing MRI’s

1 hour of MR Scanner time used for diagnostic imaging could generate $1,200⁽²⁾

1 hour of MR scanner time used for a ClearPoint procedure could generate $5,275⁽³⁾

Utilizes existing MRI’s already in hospital

(1) Medtronic Investor Presentation, June, 2014

(2) Estimated average US hospital-based MRI suite revenue per hour for outpatient diagnostic scans, based on data gathered by MRI Interventions. Excludes professional fees. Actual revenues will vary by hospital, procedure and payor.

(3) Based on a weighted average payment to MRI Interventions’ customers (as of September 2014) for an electrode placement procedure for Medicare and private insurance patients, calculated by MRI Interventions using a payor mix weighted 67% to average Medicare reimbursement and 33% to average private insurance reimbursement. Average Medicare reimbursement calculated as the weighted average Medicare payment for MRI Interventions’ customers (as of September 2014) for an electrode placement procedure under MS-DRGs 025, 026 and 027. Average private insurance reimbursement calculated as 1.5x Medicare reimbursement, based on published data. Hourly amount assumes 4.5 hour procedure duration. Excludes professional fees. Actual revenues will vary by hospital, procedure and payor.

Multi-Therapy MRI-Guided Navigational System

Leading Neurosurgeon Supporters

Dr. Philip Starr ASSFN Past President

Dr. Paul Larson UCSF & VA

Dr. Robert Gross Emory University

Dr. Robert Wharen, Jr. Mayo Clinic -Jacksonville

Dr. Krys Bankiewicz Bankiewicz Lab, UCSF

Dr. Russ Lonser OSU -NIH

Strong Peer-Reviewed Journal Support

Compatible With Multiple Therapies

SmartFlow^TM cannula for local drug delivery

Strong Intellectual Property

Close to 100 issued patents around the world

50+ U.S. Patents

45+ OUS Patents

40+ U.S. Patent Applications

50+ OUS Patent Applications

Issued patents cover areas such as: MRI-guided surgical systems that include software and devices; the SmartFrame® trajectory guide; other ClearPoint® disposable components; active intracranial probes; MRI-compatible catheters; MRI-safety technology

Key ClearPoint-related patents do not begin to expire until 2027

Patient Impact

Martin’s Story

ClearPoint-Enabled Electrode Placement

Patient Benefit Minimally Invasive Procedure

7 days after ClearPoint procedure Arrow Indicates Surgery Site

ClearPoint Drug Delivery

• MR visualization of neuro target

• MR-guided placement of catheter

• Therapeutic agent delivered under MR-guidance*

Specialized drug delivery cannula’s catheters

Drug infusion is visible real time under MRI

Conclusion: The ClearPoint system allows Real-time Convection-enhanced Delivery to be performed with a high level of precision, predictability, and safety.

*CAUTION: SmartFlow^TMCannula is approved for injection of Cytarabine or removal of CSF from the ventricles during intracranial procedures. Uses other than the approved indication are limited by Federal law to investigational use.

MRI’S Unique Opportunity in Drug Delivery

Provides MRIC with “biotech-like upside” without “all or nothing downside”

Major Challenges in Delivering Drugs to the Brain

- Blood brain barrier blocks systemic delivery of almost all drugs – 98% of small molecules

- Direct injection without ClearPoint is blind, so target is frequently missed

- Neopharm Trial - 51% of 572 catheters failed to meet all positioning criteria

Major Benefits of Drug Delivery with ClearPoint

- Neurosurgeon sees that target is reached

- Eliminates the blood brain barrier issue; Reduces/eliminates unwanted systemic side effects; Reduces dosage levels (as little as 1/300th of systemic volumes)

Business Model MRIC Partners with Drug Companies and Researchers

- MRIC provides ClearPoint; Drug company provides drug candidate

- Drug company/sponsor pays for trial

- If drug is approved, MRIC gets device revs (~$7000/case); Drug co gets drug revs

The ClearPoint Difference

Without ClearPoint (Stereotactic)

No direct visualization; Performed in anoperating room

Patient may be awake forown brain surgery(1)

Long procedures – Can be up to 8 hours

Accuracy to target based on prior images

May require OR and MRI for same procedure (laser ablation)

Poor economics for hospital and physician

With ClearPoint

Direct, high resolution visualization; Performed in an MRI Suite

Patient may be undergeneralanesthesia(1)

Shorterprocedures Can be 3 hours or less

Highly accurate, based on real time images

One procedure, one place

Attractive economics for hospital and physician

Better for Patients

Better for Surgeons

Better for Hospitals

(1) Microelectrode recording and macrostim are processes that involve listening to neuronal firings (i.e., physiological recordings) and observing physiological responses to stimuli during brain surgery. In connections with our 510(k) clearence in 2010, the FDA requested a warning within Clearpoint’s instructions for Use based on the lack of data with respect to deep brain stimulation (DBS) procedures. The warning states that the ClearPoint system, alone, should not be used to guide a DBS lead to a specific brain target and that final placement of DBS leads requires physiological recordings to confirm that they are located in the correct brain target and functioning as intended.

ClearPoint Revenue Model

BUSINESS MODEL – RAZOR / RAZORBLADE

ClearPoint Hardware/Software: $100,000 - $150,000 ASP

ClearPoint Disposables: $7,500 (average) ASP per procedure with strong margins

Recurring revenue from the sale of disposables

Procedures covered by existing inpatient DRG reimbursement codes

Growing the ClearPoint Footprint

Installed Base of 39 sites in the US

ClearPoint US Market Opportunity

Parkinson’s

Epilepsy

Brain Tumors

Total Prevalence (US)

1,500,000

2,200,000

80,000(annual diagnosis)

Prevalence – Drug Treatment Resistant (DTR)

125,000

264,000

Incidence – DTR

7,500

18,000

Resections: 80,000 Stereotactic Biopsy: 10,000

ClearPoint Enabled Therapy

Electrode Placement (DBS)

Laser AblationRNS1

Biopsy / Laser Ablation / Drug Delivery

Potential ClearPoint Procedures, Annually2

12,500

28,000

14,500

55,000+ Potential Procedures Per Year

Note: Prevalence and Incidence based on either market research conducted by a third party on behalf of MRI Interventions or research conducted by MRI Interventions of publicly available sources.

(1) Responsive neurostimulation device (RNS)

(2) Potential Annual ClearPoint Procedures based upon 5% of prevalence and 85% of incidence; Potential Annual ClearPoint Procedures for brain tumors based on market research conducted by a third party on behalf of MRI Interventions.

ClearPoint Future Opportunities Multiple Therapies for Future Growth

Neuro Disorder

Patient Population

Treatment Resistant Patient Population

ClearPoint Enabled Therapy

Current Status

Dystonia

250,000

25,000

DBS

Active Use, HDE

OCD

3,300,300

100,000

DBS

Active Use, HDE

Severe Depression

6,000,000

1,200,000

DBS

IDE Trials (DBS)

Parkinson’s Disease

1,500,000

125,000

Drug Delivery

Clinical Trials – Phase 1

Brain Tumors (GBM)

11,000

Drug Delivery

Clinical Trials – Phase 1

Huntington’s

30,000

Drug Delivery

Pre-Clinical

ALS

30,000

Drug Delivery

Pre-Clinical

Alzheimer's

5,400,000

500,000

DBS

Research

ClearPoint Consumable Revenues

Consumable Revenue

$1,200,000 $1,000,000 $800,000 $600,000 $400,000 $200,000

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3

2013 2014 2015

Total Revenue, 2013 - 2015

$1,400,000

Total Revenue

$1,200,000 $1,000,000 $800,000 $600,000 $400,000 $200,000

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3

2013 2014 2015

Consumables Capital / Service Other

Cash Flow From Operations

$0 -$500,000 -$1,000,000 -$1,500,000 -$2,000,000 -$2,500,000

-$3,000,000

Q1 Q2 Q3 Q4 Q1 Q2

2014 2015

Commercial Priorities

Increase Utilization

• Focus on adding surgeons at existing accounts

• Target high volume sites, including epilepsy and tumor neurosurgeons within each account; gain greater share of their procedures

• Add Clinical Specialists and sales reps to commercial team; compensate for utilization growth

Enhance Communication

• Increase peer-to-peer events, presence at trade shows

• Highlight existing data on ClearPoint applications to neurologists and neurosurgeons

• Communicate value proposition across procedures:

• Accuracy

• Real time visualization

• Improved workflow

• Increase patient volume

Expand Account Base

• Identify highest volume potential accounts across multiple procedures

• Support local hospital marketing efforts

• Capitalize on interest in drug delivery to expand in oncology accounts

• Add sales reps

Achieve Cash Breakeven

• Tightly control working capital, consumption of cash

• Hire additional personnel only in key functions – commercial team; engineering

R&D Priorities

Software 2.0

• Significant upgrade to existing software; includes real time fusion, enhanced graphic and User Interface

• Technology licenses near complete with three additional software companies for this effort

OR SmartFrame

• Through partnership(s), expand our products and brand into the operating room for CT based neuro procedures

Drug Delivery

• Establish additional drug delivery partnerships, and participate in additional clinical trials

• Become the neuro drug delivery device partner of choice

Procedure Enhancements

• Continue to enhance product line with a focus on procedure simplification and consistency

Bolt Driver for Laser Ablation

At the Center of an Emerging Industry Trend

ClearPoint Electrode Placement

ClearPoint Laser Catheter Placement

ClearPoint Performed in MRI Scanners

ClearTrace Ablation and Drug Delivery

ClearPoint Direct Drug Delivery

Real Time MRI-Guided Procedures

MRIC is at the point of convergence in an industry trend impacting some of the most influential and innovative medical device companies in the world

Ticker: MRIC

MRI Interventions, Inc.

Irvine, CA 949.900.6833

mriinterventions.com

Transforming minimally invasive neurosurgery by enabling real-time visualization with MRI