Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Stockholders' Equity (Deficit)

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Consolidated Statements of Stockholders' Equity (Deficit) - USD ($)
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Deficit [Member]
Total
Balances at beginning at Dec. 31, 2015 $ 22,845 $ 83,722,596 $ (85,726,580) $ (1,981,139)
Balances at beginning (in shares) at Dec. 31, 2015 2,284,537      
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Issuances of common stock in Share-based compensation $ 291 1,186,809   1,187,100
Issuances of common stock in Share-based compensation (in shares) 29,117      
Issuances of common stock in payment of expenses $ 44 62,686   62,730
Issuances of common stock in payment of expenses (in shares) 4,375      
Issuances of common stock in connection with debt restructuring $ 993 1,347,727   1,348,720
Issuances of common stock in connection with debt restructuring (in shares) 99,310      
Issuances of common stock Warrant exercise $ 42 37,630   37,672
Issuances of common stock Warrant exercise (in shares) 4,245      
Creation of derivative liabilities in connection with note and warrant restructuring     (72,289) (72,289)
Cash paid in lieu of issuing fractional shares in reverse split of common stock $ (5) (4,755)   (4,760)
Cash paid in lieu of issuing fractional shares in reverse split of common stock (in shares) (552)      
Private placement, net of offering costs $ 12,010 5,635,350   5,647,360
Private placement, net of offering costs (in shares) 1,201,000      
Transfer of fair value of derivative liabilities upon conversion of related debt in connection with private placement   1,088,432   1,088,432
Net loss for the year     (8,069,895) (8,069,895)
Balances at end at Dec. 31, 2016 $ 36,220 93,076,475 (93,868,764) (756,069)
Balances at end (in shares) at Dec. 31, 2016 3,622,032      
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Issuances of common stock in Share-based compensation $ 3,544 1,242,057   1,245,601
Issuances of common stock in Share-based compensation (in shares) 354,391      
Issuances of common stock in payment of expenses $ 883 501,149   502,032
Issuances of common stock in payment of expenses (in shares) 88,333      
Issuances of common stock Warrant exercise $ 40 11,169   11,209
Issuances of common stock Warrant exercise (in shares) 4,095      
Private placement, net of offering costs $ 66,250 11,927,070   11,993,320
Private placement, net of offering costs (in shares) 6,625,000      
Net loss for the year     (7,167,353) (7,167,353)
Balances at end at Dec. 31, 2017 $ 106,937 $ 106,757,920 $ (101,036,117) $ 5,828,740
Balances at end (in shares) at Dec. 31, 2017 10,693,851