Quarterly report pursuant to Section 13 or 15(d)

Description of the Business and Liquidity (Details Narrative)

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Description of the Business and Liquidity (Details Narrative) - USD ($)
 1 Months Ended 3 Months Ended
May 31, 2017
Mar. 31, 2018
Dec. 31, 2017
Mar. 31, 2017
Dec. 31, 2016
Cumulative net loss   $ (102,677,034) $ (101,036,117)    
Cash and cash equivalents   7,513,634 $ 9,289,831 $ 1,969,597 $ 3,315,774
Notes Payable [Member]          
Debt face amount   4,000,000      
Notes Payable [Member] | Notes Payable Matures December 2018 [Member]          
Debt face amount   $ 2,000,000      
Maturity date   Dec. 31, 2018      
Notes Payable [Member] | Notes Payable Matures March 2019 [Member]          
Debt face amount   $ 2,000,000      
Maturity date   Mar. 31, 2019      
2017 Private Placement [Member]          
Proceeds from issuance of private placement $ 13,250,000        
Agents' fees and offering expenses $ 1,300,000