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Note 1 - Description of the Business and Liquidity (Details) (USD $)
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1 Months Ended | 12 Months Ended | 1 Months Ended | 12 Months Ended | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
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Jan. 31, 2013
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Jul. 31, 2012
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Feb. 29, 2012
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Nov. 30, 2010
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Dec. 31, 2013
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Dec. 31, 2012
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Dec. 31, 2011
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Mar. 31, 2014
Subsequent Event [Member]
Boston Scientific Notes [Member]
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Mar. 31, 2014
Subsequent Event [Member]
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Dec. 31, 2012
Unit Offering Completed in February 2012 [Member]
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Dec. 31, 2011
Unit Offering Completed in February 2012 [Member]
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| Note 1 - Description of the Business and Liquidity (Details) [Line Items] | |||||||||||
| Net Income (Loss) Attributable to Parent | $ (7,086,274) | $ (5,877,718) | |||||||||
| Retained Earnings (Accumulated Deficit) | (72,752,602) | (65,666,328) | |||||||||
| Net Cash Provided by (Used in) Operating Activities | (7,777,931) | (7,433,816) | |||||||||
| Proceeds from Issuance of Private Placement | 9,829,014 | 5,516,495 | 9,829,014 | 5,516,495 | 3,400,000 | ||||||
| Development Stage Entities, Stock Issued, Value, Issued for Cash | 4,946,560 | ||||||||||
| Proceeds from Issuance or Sale of Equity | 3,000,000 | 3,424,950 | 1,521,610 | ||||||||
| Notes Payable Cancelled, Principal Amount | 4,338,601 | ||||||||||
| Cash and Cash Equivalents, at Carrying Value | $ 3,516,244 | $ 1,620,005 | $ 145,478 | ||||||||
| X | ||||||||||
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- Details
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| X | ||||||||||
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- Definition
The aggregate principal amount of notes payable cancelled No definition available.
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| X | ||||||||||
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- Definition
Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Amount of cash inflow (outflow) from operating activities, including discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
The portion of profit or loss for the period, net of income taxes, which is attributable to the parent. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
The cash inflow associated with the amount received from entity's raising of capital via private rather than public placement. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
The cash inflow from the issuance of common stock, preferred stock, treasury stock, stock options, and other types of equity. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
The cumulative amount of the reporting entity's undistributed earnings or deficit. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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| X | ||||||||||
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- Definition
Value of shares issued as consideration for cash for development stage entities. Reference 1: http://www.xbrl.org/2003/role/presentationRef
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