Annual report pursuant to Section 13 and 15(d)

Description of the Business and Financial Condition (Details Narrative)

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Description of the Business and Financial Condition (Details Narrative) - USD ($)
1 Months Ended
May 31, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Cumulative net loss   $ 101,036,117 $ 93,868,764  
Cash and cash equivalents   $ 9,289,831 $ 3,315,774 $ 5,408,523
2017 Private Placement [Member]        
Proceeds from issuance of private placement $ 13,250,000      
Agents' fees and offering expenses $ 1,300,000